In 1878, Stockholms Högskola (today Stockholm University) was founded to promote scientific research and ensure that Sweden did not fall behind in this field. The old state universities were considered to be engaged in very traditional subjects, such as the humanities and theology. Inspiration for the university was taken from France and England. Initially, education in mathematics, physics, chemistry and geology, was given, but soon zoology and botany were added to that list.

The fact that the institution was called Stockholms Högskola was a sign that the university differed from the other state universities, that it was an independent institution primarily focused on natural sciences. Its uniqueness was further marked by hiring Sweden's, and probably Europe's, first female professor of mathematics, Sonja Kovalevsky.

As early as the 1890s, students founded a student union. Its members and leaders were, of course, natural science students as these were the only students at the university. At the beginning of the 20th century, the university’s program catalogue was expanded to also include law and the humanities. As humanists and lawyers started at the university, the student body became mixed, and a power struggle flared up: the natural science students believed that the jurists engaged in "fruitless discussions and dialectal exercises". After a few years, the lawyers lead the student union. As a result, the natural scientists and humanists broke out of the student union in 1914 and formed their own faculties, today the Natural Sciences Faculty Club and the Humanities Faculty Club. The frog became NF's symbol when a man named Ebbe Linde started singing "Små grodorna" as a chant during a Christmas party in the newly started department. "Små grodorna" also became our battle song.

At this time, Stockholms Högskola was spread out in central Stockholm. As the university grew, a search for a place to gather the institution at began. The university also began to have financial problems as the number of students and the demand for expensive equipment for research increased. In 1960, it was decided that Stockholms Högskola would become Stockholm University, and that it would be run by the state. It also started planning for a move to Frescati, where the former agricultural academy had its premises.

The Natural Sciences Faculty Club also grew during these years, with the exception of a few years in the stormy 70s when the Natural Sciences Faculty Club's activities were almost null. At this time, unfortunately, most of the Natural Sciences Faculty Club's archives also disappeared, and NF led a dwindling existence until some zealots started the association again in the early 80's.

Over the years, the faculty club has been located in a number of different places around Stockholm, including at Observatoriekullen by the City Library where we stayed until 1992 when the move out to Frescati was made. Here, the faculty was first housed in the upstairs of Gula Villan. In 2005, we took over our current premises, Gréen's Villa.